PHGDH Induction by MAPK Is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability

Neel Jasani(University of South Florida), Florian A. Karreth(Moffitt Cancer Center)

Cancer Research

November 4, 2024

10.1158/0008-5472.can-24-2471

Cited by 8

Related Papers

Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under<i>in vitro</i>conditions

|Platelets|2004|182

BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model

|Proceedings of the National Academy of Sciences|2015|143

Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer

|Cancer Discovery|2017|76

A versatile ES cell-based melanoma mouse modeling platform

|bioRxiv (Cold Spring Harbor Laboratory)|2019|4

MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability

|bioRxiv (Cold Spring Harbor Laboratory)|2024|0