Vitessce: integrative visualization of multimodal and spatially resolved single-cell data

Mark S. Keller(Harvard University), Ilan Gold(Harvard University), Chuck McCallum(Harvard University), Trevor Manz(Harvard University), Peter V. Kharchenko(Broad Institute), Nils Gehlenborg(Harvard University)
Nature Methods
September 27, 2024
Cited by 57Open Access
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Abstract

Multiomics technologies with single-cell and spatial resolution make it possible to measure thousands of features across millions of cells. However, visual analysis of high-dimensional transcriptomic, proteomic, genome-mapped and imaging data types simultaneously remains a challenge. Here we describe Vitessce, an interactive web-based visualization framework for exploration of multimodal and spatially resolved single-cell data. We demonstrate integrative visualization of millions of data points, including cell-type annotations, gene expression quantities, spatially resolved transcripts and cell segmentations, across multiple coordinated views. The open-source software is available at http://vitessce.io .


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