Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation

Hongyu Chen(Broad Institute), Dangliang Liu(Broad Institute), Abhishek Aditham(Broad Institute), Jianting Guo(Broad Institute), Jiahao Huang(Broad Institute), Franklin Kostas(Broad Institute), Kamal Maher(Broad Institute), Mirco Friedrich(Broad Institute), Ramnik J. Xavier(Broad Institute), Feng Zhang(Broad Institute), Xiao Wang(Broad Institute)
Nature Biotechnology
September 23, 2024
10.1038/s41587-024-02393-y
Cited by 71Open Access
Full Text

Abstract

Related Papers

The mechanism of eukaryotic translation initiation and principles of its regulation
Richard J. Jackson, Christopher U.T. Hellen, Tatyana V. Pestova|Nature Reviews Molecular Cell Biology|2010|2.8k
Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
Katalin Karikó, Hiromi Muramatsu, Frank A. Welsh et al.|Molecular Therapy|2008|1.8k
Electrophoretic mobility shift assay (EMSA) for detecting protein–nucleic acid interactions
Lance M. Hellman, Michael G. Fried|Nature Protocols|2007|1.2k
Deep proteome and transcriptome mapping of a human cancer cell line
Nagarjuna Nagaraj, Jacek R. Wiśniewski, Tamar Geiger et al.|Molecular Systems Biology|2011|1k
Internal ribosome entry sites in eukaryotic mRNA molecules
Christopher U.T. Hellen, Peter Sarnow|Genes & Development|2001|985