Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization
Satoshi Kaito(National Cancer Centre Japan), Atsushi Iwama(Chiba University), Masayuki Yamashita(Kyoto Pharmaceutical University), Kimihito C. Kawabata(The University of Tokyo), Kristian Helin(University of Copenhagen), Kiyoshi Yamaguchi(Tokyo Medical University), Yoichi Furukawa(The University of Tokyo), Yuka Harada(Tokyo Metropolitan Komagome Hospital), Noriko Doki(Tokyo Metropolitan Komagome Hospital), Makoto Nakanishi(The Cancer Institute Hospital), Hironori Harada(Tokyo University of Pharmacy and Life Sciences), Seishi Ogawa(Keio University), Hidetaka Kosako(Institute for Advanced Medical Research), Ryoji Ito(Central Institute for Experimental Animals), Hiroko Kozuka‐Hata(Systems Biology Institute), Karl Agger(University of Copenhagen), Kazumasa Aoyama(Keio University), Takao Yogo(The University of Tokyo), Tomohiro Yabushita(The University of Tokyo), Makiko Miyota(The University of Tokyo), Kaoru Tohyama(Kawasaki Medical School), Yasuhito Nannya(Kyoto University), Akihide Yoshimi(Memorial Sloan Kettering Cancer Center), Shuhei Koide(The University of Tokyo), Masaya Ueno, Masaaki Oyama(The University of Tokyo), Susumu Goyama(The University of Tokyo), Atsuya Nishiyama(The University of Tokyo), Haruhiko Koseki(RIKEN Center for Integrative Medical Sciences), Atsushi Hirao(Kanazawa University), Satoshi Yamazaki(University of Tsukuba), Motohiko Oshima(The University of Tokyo), Yaeko Nakajima-Takagi(The University of Tokyo), Chao Li(The University of Tokyo), Akiho Tsuchiya(The University of Tokyo)
Cited by 22
Related Papers
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data
|Blood|2022|2.8k
Ubiquitin is phosphorylated by PINK1 to activate parkin
|Nature|2014|1.5k
Navigating the DNA methylation landscape of cancer
|Trends in Genetics|2021|1k
Role of TET enzymes in DNA methylation, development, and cancer
|Genes & Development|2016|1k