Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity
Kate M. Saville(USA Mitchell Cancer Institute), Robert W. Sobol(Brown University)
Cited by 7
Related Papers
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
|Proceedings of the National Academy of Sciences|2013|644
Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin
|Nucleic Acids Research|2013|101
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity
|Scientific Reports|2020|92
NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells
|NAR Cancer|2021|31
Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage
|Methods in molecular biology|2022|8