The Virtual Child
Richard J. Gilbertson(University of Cambridge), Sam Behjati(University of Cambridge), Anna-Lisa Böttcher(German Cancer Research Center), Marianne Bronner‐Fraser(California Institute of Technology), Matthew Burridge, Henrick Clausing(TherapySelect (Germany)), Harry Clifford(Nvidia (United Kingdom)), Tracey S. Danaher(Children's Cancer Institute Australia), Laura Donovan(Great Ormond Street Hospital), Jarno Drost(Utrecht University), Alexander M.M. Eggermont(Princess Máxima Center), Chris Emerson(Nvidia (United Kingdom)), Mona G. Flores(Nvidia (United States)), Petra Hamerlik(University of Manchester), Nada Jabado(McGill University Health Centre), A. S. Jones, Henrick Kaessmann(Heidelberg University), Claudia L. Kleinman(Jewish General Hospital), Marcel Kool(German Cancer Research Center), Lena M. Kutscher(German Cancer Research Center), Gavin Lindberg(Dermatology Foundation), Emily Linnane(University of Cambridge), John C. Marioni(European Bioinformatics Institute), John M. Maris(Children's Hospital of Philadelphia), Michelle Monje(Stanford University), Alexandra Macaskill(Molecular Oncology (United States)), Steven Niederer(Turing Institute), Paul A. Northcott(St. Jude Children's Research Hospital), Elizabeth Peeters(SickKids Foundation), Willemijn Plieger-van Solkema(Netherlands Comprehensive Cancer Organisation), Liane Preußner(Institut zur Förderung von Bildung und Integration), Anne C. Rios(Princess Máxima Center), Karsten Rippe(German Cancer Research Center), Peter Sandford, Nikolaos G. Sgourakis(Children's Hospital of Philadelphia), Adam Shlien(Hospital for Sick Children), Pete Smith(Translational Therapeutics (United States)), Karin Straathof(Great Ormond Street Hospital), P. J. E. Sullivan(Vancouver Foundation), Mario L. Suvà(Broad Institute), Michael D. Taylor(Children's Cancer Center), E. Thompson(Brain Tumour Charity), Roser Vento‐Tormo(Wellcome Sanger Institute), Brandon J. Wainwright(Translational Research Institute), Robert J. Wechsler‐Reya(Columbia University Irving Medical Center), Frank Westermann(German Cancer Research Center), Shannon Winslade(Brain Tumour Charity), Bissan Al‐Lazikani(The University of Texas MD Anderson Cancer Center), Stefan M. Pfister(German Cancer Research Center)
Cited by 7Open Access
Abstract
SUMMARY: We are building the world's first Virtual Child-a computer model of normal and cancerous human development at the level of each individual cell. The Virtual Child will "develop cancer" that we will subject to unlimited virtual clinical trials that pinpoint, predict, and prioritize potential new treatments, bringing forward the day when no child dies of cancer, giving each one the opportunity to lead a full and healthy life.
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