predicted microRNA target sites (miRanda)

Abstract

Target predictions based on the miRanda algorithm. The target sites are scored for likelihood of mRNA downregulation using mirSVR, a regression model that is trained on sequence and contextual features of the predicted miRNA::mRNA duplex. Expression profiles are derived from a comprehensive sequencing project of a large set of mammalian tissues and cell lines of normal and disease origin. This collection contains the following datasets from the August 2010 release of microRNA.org: 16228619 predicted microRNA target sites in 34911 distinct 3'UTR from isoforms of 19898 human genes 7459149 predicted microRNA target sites in 28287 distinct 3'UTR from isoforms of 19231 mouse genes 586068 predicted microRNA target sites in 6865 distinct 3'UTR from isoforms of 6256 rat genes 345671 predicted microRNA target sites in 12285 distinct 3'UTR from isoforms of 10532 fruitfly genes