The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-<i>N</i>-(6-methylpyrazolo[1,5-<i>a</i>]pyrimidin-3-yl)imidazo[1,2-<i>a</i>]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke
Ryan Evans(Biogen (United States)), Emily A. Peterson(Biogen (United States)), Philippe N. Bolduc(Biogen (United States)), Claire M. Metrick(Biogen (United States)), Patrick Trapa(Biogen (United States)), Ashley N. Nelson(Cornell University), Ankur Thomas(Biogen (United States)), Terry Fang(Biogen (United States)), Brian T. Hopkins(Biogen (United States)), Tricia L. May‐Dracka(Biogen (United States)), Magnus Pfaffenbach(Biogen (United States)), Pei Li(Biogen (United States)), Fang Gao(Biogen (United States)), Kate L. Henry(Biogen (United States)), Jayanth V. Chodaparambil(Colorado State University), Linda C. Burkly(Biogen (United States))
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