Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D

Qinheng Zheng(Scripps Research Institute), Kevan M. Shokat(Howard Hughes Medical Institute), Keelan Z. Guiley(Howard Hughes Medical Institute), Ziyang Zhang(University of California, Berkeley)
Nature Chemical Biology
March 5, 2024
10.1038/s41589-024-01565-w
Cited by 71

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