Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity during Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT).

John F. DiPersio(Washington University in St. Louis), Guenther Koehne(Baptist Hospital of Miami), Brenda Cooper(University Hospitals Cleveland Medical Center), Divya Koura(University of California San Diego), Nirali N. Shah(National Institutes of Health), Hyung C. Suh(Science Applications International Corporation (United States)), Glen Raffel(University of Massachusetts Chan Medical School), Kyle Breitschwerdt, Michael R. Loken(Unknown), Sritama Nath(University of North Carolina at Charlotte), Miguel‐Angel Perales(Memorial Sloan Kettering Cancer Center), Roni Tamari(Memorial Sloan Kettering Cancer Center), Markus Y. Mapara(Sheba Medical Center), Léa Bernard(Hôpital Maisonneuve-Rosemont), Roland B. Walter(Rafael Advanced Defense Systems (Israel))
Transplantation and Cellular Therapy
February 1, 2024
Cited by 7


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