Metformin reduces the clonal fitness of Dnmt3aR878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state
Steven M. Chan(Princess Margaret Cancer Centre), Jennifer J. Trowbridge(Jackson Laboratory), Gary D. Bader(University of Toronto), Séverine Cathelin(Princess Margaret Cancer Centre), Véronique Voisin(University of Toronto), Samuele Ferrari(Vita-Salute San Raffaele University), Mohsen Hosseini(Princess Margaret Cancer Centre), Angelica Varesi(The San Raffaele Telethon Institute for Gene Therapy), Angelo D’Alessandro(University of Colorado Anschutz Medical Campus), Aaron D. Schimmer(University of Toronto), Alex C.H. Liu(University of Toronto), Kira Young(Jackson Laboratory), Stephanie Z. Xie(Princess Margaret Cancer Centre), Luigi Naldini(Vita-Salute San Raffaele University), Dhanoop Manikoth Ayyathan(Princess Margaret Cancer Centre), Federico Gaiti(University of Toronto), John E. Dick(University of Toronto), Ali Chegini(University of Toronto), Shraddha Pai(Ontario Institute for Cancer Research), Yiyan Wu(University of Toronto), Yitong Yang, Vivian Wang(University of Toronto), Abdula Maher(Princess Margaret Cancer Centre), Éric Grignano(Centre National de la Recherche Scientifique), Julie Haines, Martina Fiumara(The San Raffaele Telethon Institute for Gene Therapy)
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