Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance

Hao Zheng; Jinming Liu; Qi Cheng; Qianping Zhang; Yaoyao Zhang; Lingyu Jiang; Yan Huang; Wenlei Li; Yanping Zhao; Guo Chen; Yu Fan; Lei Liu; Yanjun Li; Xudong Liao; Lai Xu; Yi Xiao; Zhibo Zheng; Ming Li; Hongyi Wang; Gang Hu; Lei Du; Quan Chen

doi:10.1038/s43018-023-00715-8

Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance

Hao Zheng(Nankai University), Jinming Liu(Nankai University), Qi Cheng(Chinese Academy of Sciences), Qianping Zhang(Nankai University), Yaoyao Zhang(Nankai University), Lingyu Jiang(Nankai University), Yan Huang(Nankai University), Wenlei Li(Nankai University), Yanping Zhao(Nankai University), Guo Chen(Nankai University), Yu Fan(Nankai University), Lei Liu(Chinese Academy of Sciences), Yanjun Li(Nankai University), Xudong Liao(Nankai University), Lai Xu(Chinese Academy of Medical Sciences & Peking Union Medical College), Yi Xiao(Chinese Academy of Medical Sciences & Peking Union Medical College), Zhibo Zheng(Chinese Academy of Medical Sciences & Peking Union Medical College), Ming Li(Peking University), Hongyi Wang(Peking University), Gang Hu(Nankai University), Lei Du(Nankai University), Quan Chen(Nankai University)

Nature Cancer

January 30, 2024

10.1038/s43018-023-00715-8

Cited by 105

Abstract

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