The fragile X locus is prone to spontaneous DNA damage that is preferentially repaired by nonhomologous end-joining to preserve genome integrity

Daman Kumari(National Institute of Diabetes and Digestive and Kidney Diseases), Karen Usdin(National Institute of Diabetes and Digestive and Kidney Diseases)
iScience
January 6, 2024
10.1016/j.isci.2024.108814
Cited by 5

Related Papers

The biological effects of simple tandem repeats: Lessons from the repeat expansion diseases: Table 1.
|Genome Research|2008|281
A common flanking variant is associated with enhanced stability of the FGF14-SCA27B repeat locus
|Nature Genetics|2024|34
Repeat expansion in a fragile X model is independent of double strand break repair mediated by Pol θ, RAD52, RAD54 or RAD54B
|Scientific Reports|2025|2
Repeat expansion in a Fragile X model is independent of double strand break repair mediated by Pol θ, Rad52, Rad54l or Rad54b
|bioRxiv (Cold Spring Harbor Laboratory)|2024|1
MSH2 is not required for either maintenance of DNA methylation or repeat contraction at the FMR1 locus in fragile X syndrome or the FXN locus in Friedreich’s ataxia
|Epigenetics & Chromatin|2025|1