Ensembl 2024

Peter W. Harrison(European Bioinformatics Institute), M Ridwan Amode(European Bioinformatics Institute), Olanrewaju Austine-Orimoloye(European Bioinformatics Institute), Andrey G Azov(European Bioinformatics Institute), Matthieu Barba(European Bioinformatics Institute), If Barnes(European Bioinformatics Institute), Arne Becker(European Bioinformatics Institute), Ruth Bennett(European Bioinformatics Institute), Andrew Berry(European Bioinformatics Institute), Jyothish Bhai(European Bioinformatics Institute), Simarpreet Kaur Bhurji(European Bioinformatics Institute), Sanjay Boddu(European Bioinformatics Institute), Paulo Lins(European Bioinformatics Institute), Lucy Brooks(European Bioinformatics Institute), Shashank Budhanuru Ramaraju(European Bioinformatics Institute), Lahcen Campbell(European Bioinformatics Institute), Manuel Carbajo Martinez(European Bioinformatics Institute), Mehrnaz Charkhchi(European Bioinformatics Institute), Kapeel Chougule(Cold Spring Harbor Laboratory), Alexander Cockburn(European Bioinformatics Institute), Claire Davidson(European Bioinformatics Institute), Nishadi De Silva(European Bioinformatics Institute), Kamalkumar Dodiya(European Bioinformatics Institute), Sarah Donaldson(European Bioinformatics Institute), Bilal El Houdaigui(European Bioinformatics Institute), Tamara El Naboulsi(European Bioinformatics Institute), Reham Fatima(European Bioinformatics Institute), Carlos García Girón(European Bioinformatics Institute), Thiago A. L. Genez(European Bioinformatics Institute), Dionysios Grigoriadis(European Bioinformatics Institute), Gurpreet S Ghattaoraya(European Bioinformatics Institute), José M. González(European Bioinformatics Institute), Tatiana A. Gurbich(European Bioinformatics Institute), Matthew P. Hardy(European Bioinformatics Institute), Zoe Hollis(European Bioinformatics Institute), Thibaut Hourlier(European Bioinformatics Institute), Toby Hunt(European Bioinformatics Institute), Mike Kay(European Bioinformatics Institute), Vinay Kaykala(European Bioinformatics Institute), Anh Tuấn Lê(European Bioinformatics Institute), Diana Lemos(European Bioinformatics Institute), Disha Lodha(European Bioinformatics Institute), Diego Marques‐Coelho(European Bioinformatics Institute), G. Maslen(European Bioinformatics Institute), Gabriela Merino(European Bioinformatics Institute), Louisse Paola Mirabueno(European Bioinformatics Institute), Aleena Mushtaq(European Bioinformatics Institute), Syed Nakib Hossain(European Bioinformatics Institute), Denye Ogeh(European Bioinformatics Institute), Manoj Pandian Sakthivel(European Bioinformatics Institute), Anne Parker(European Bioinformatics Institute), Malcolm Perry(European Bioinformatics Institute), Ivana Piližota(European Bioinformatics Institute), Daniel Poppleton(European Bioinformatics Institute), Irina Prosovetskaia(European Bioinformatics Institute), Shriya Raj(European Bioinformatics Institute), José G Pérez-Silva(European Bioinformatics Institute), Ahamed Imran Abdul Salam(European Bioinformatics Institute), Shradha Saraf(European Bioinformatics Institute), Nuno Saraiva-Agostinho(European Bioinformatics Institute), Dan Sheppard(European Bioinformatics Institute), Swati Sinha(European Bioinformatics Institute), Botond Sipos(European Bioinformatics Institute), Vasily Sitnik(European Bioinformatics Institute), William Stark(European Bioinformatics Institute), Emily Steed(European Bioinformatics Institute), Marie‐Marthe Suner(European Bioinformatics Institute), Likhitha Surapaneni(European Bioinformatics Institute), Kyösti Sutinen(European Bioinformatics Institute), Francesca Floriana Tricomi(European Bioinformatics Institute), David Urbina-Gómez(European Bioinformatics Institute), Andres Veidenberg(European Bioinformatics Institute), Thomas Walsh(European Bioinformatics Institute), Doreen Ware(Agricultural Research Service), Elizabeth Wass(European Bioinformatics Institute), Natalie L Willhoft(European Bioinformatics Institute), Jamie Allen(European Bioinformatics Institute), Jorge Álvarez-Jarreta(European Bioinformatics Institute), Marc Chakiachvili(European Bioinformatics Institute), Bethany Flint(European Bioinformatics Institute), Stefano Giorgetti(European Bioinformatics Institute), Leanne Haggerty(European Bioinformatics Institute), Garth R Ilsley(European Bioinformatics Institute), Jon Keatley(European Bioinformatics Institute), Jane Loveland(European Bioinformatics Institute), Benjamin Moore(European Bioinformatics Institute), Jonathan M. Mudge(European Bioinformatics Institute), Guy Naamati(European Bioinformatics Institute), John Tate(European Bioinformatics Institute), Stephen J. Trevanion(European Bioinformatics Institute), Andrea Winterbottom(European Bioinformatics Institute), Adam Frankish(European Bioinformatics Institute), Sarah Hunt(European Bioinformatics Institute), Fiona Cunningham(European Bioinformatics Institute), Sarah Dyer(European Bioinformatics Institute), ROBERT FINN(European Bioinformatics Institute), Fergal J. Martin(European Bioinformatics Institute), Andrew Yates(European Bioinformatics Institute)
Nucleic Acids Research
November 11, 2023
10.1093/nar/gkad1049
Cited by 714Open Access
Full Text

Abstract

Ensembl (https://www.ensembl.org) is a freely available genomic resource that has produced high-quality annotations, tools, and services for vertebrates and model organisms for more than two decades. In recent years, there has been a dramatic shift in the genomic landscape, with a large increase in the number and phylogenetic breadth of high-quality reference genomes, alongside major advances in the pan-genome representations of higher species. In order to support these efforts and accelerate downstream research, Ensembl continues to focus on scaling for the rapid annotation of new genome assemblies, developing new methods for comparative analysis, and expanding the depth and quality of our genome annotations. This year we have continued our expansion to support global biodiversity research, doubling the number of annotated genomes we support on our Rapid Release site to over 1700, driven by our close collaboration with biodiversity projects such as Darwin Tree of Life. We have also strengthened support for key agricultural species, including the first regulatory builds for farmed animals, and have updated key tools and resources that support the global scientific community, notably the Ensembl Variant Effect Predictor. Ensembl data, software, and tools are freely available.

Related Papers

Database resources of the National Center for Biotechnology Information: update
David Wheeler|Nucleic Acids Research|2003|11k
The Ensembl Variant Effect Predictor
William McLaren, Laurent Gil, Sarah Hunt et al.|Genome biology|2016|8.7k
ClinVar: improving access to variant interpretations and supporting evidence
Melissa Landrum, Jennifer M. Lee, Mark J. Benson et al.|Nucleic Acids Research|2017|4.4k
Towards complete and error-free genome assemblies of all vertebrate species
Arang Rhie, Shane McCarthy, Olivier Fédrigo et al.|Nature|2021|3k
Effective gene expression prediction from sequence by integrating long-range interactions
Žiga Avsec, Vikram Agarwal, Daniel Visentin et al.|Nature Methods|2021|1.2k