Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma

Mathew R. Schnorenberg(University of Chicago), Katrina M. Hawley(University of Chicago), Anika Thomas-Toth(University of Chicago), Elyse A. Watkins(University of Chicago), Yu Tian(University of Chicago), Jeffrey Ting(University of Chicago), Logan B. Leak(University of Chicago), Isadora M. Kucera(University of Chicago), Michal M. Raczy(University of Chicago), Andrew L. Kung(Memorial Sloan Kettering Cancer Center), Jeffrey A. Hubbell(University of Chicago), Matthew Tirrell(University of Chicago), James L. LaBelle(University of Chicago)
ACS Nano
September 9, 2023
10.1021/acsnano.3c04112
Cited by 13Open Access
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Abstract

, and synergistic dual intrinsic apoptotic therapy against DLBCL via direct p53 reactivation and BCL-2 family modulation.

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