Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification

Jayoung Ryu(Broad Institute), Sam Barkal(Brigham and Women's Hospital), Tian Yu(Brigham and Women's Hospital), Martin Jankowiak(Broad Institute), Yunzhuo Zhou(Baker Heart and Diabetes Institute), Matthew Francoeur(Brigham and Women's Hospital), Quang Vinh Phan(Brigham and Women's Hospital), Lara Brown(Brigham and Women's Hospital), Zhijian Li(Broad Institute), Manuel Tognon(Broad Institute), Michael I. Love(University of North Carolina at Chapel Hill), Guillaume Lettre(Montreal Heart Institute), David B. Ascher(Baker Heart and Diabetes Institute), Christopher A. Cassa(Brigham and Women's Hospital), Richard I. Sherwood(Brigham and Women's Hospital), Luca Pinello(Brigham and Women's Hospital)
Zenodo (CERN European Organization for Nuclear Research)
August 21, 2023
Cited by 2Open Access
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Abstract

Data repository for the paper` Joint genotypic and phenotypic outcome modeling improves base editing variant effect measurement`. Includes data required to reproduce analysis in the manuscript through the workflow in https://github.com/pinellolab/bean_manuscript.


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