A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria
Dongliang Guan(Yantai University), Wei Huang(Chinese Academy of Sciences), Lefu Lan(Chinese Academy of Sciences), Xinxin Feng(Hunan University), Xiaolei Bian, Yue Yu(Hunan University), Jian Li(Huaian First People’s Hospital), Feifei Chen(Xuzhou Medical College), Jiaqi Li(Dana-Farber Cancer Institute)
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