Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

Yogesh Goyal; Gianna T. Busch; Maalavika Pillai; Jingxin Li; Ryan H. Boe; Emanuelle I. Grody; Manoj Chelvanambi; Ian Dardani; Benjamin Emert; Nicholas Bodkin; Jonas Braun; Dylan Fingerman; Amanpreet Kaur; Naveen Jain; Pavithran T. Ravindran; Ian A. Mellis; Karun Kiani; Gretchen M. Alicea; Mitchell E. Fane; S. Ahmed; Haiyin Li; Yeqing Chen; Cedric Chai; Jessica Kaster; Russell G. Witt; Rossana Lazcano; Davis R. Ingram; Sarah B. Johnson; Khalida Wani; Margaret C. Dunagin; Alexander J. Lazar; Ashani T. Weeraratna; Jennifer A. Wargo; Meenhard Herlyn; Arjun Raj

doi:10.1038/s41586-023-06342-8

Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

Yogesh Goyal(Northwestern University), Gianna T. Busch(University of Pennsylvania), Maalavika Pillai(Northwestern University), Jingxin Li(University of Pennsylvania), Ryan H. Boe(University of Pennsylvania), Emanuelle I. Grody(Northwestern University), Manoj Chelvanambi(The University of Texas MD Anderson Cancer Center), Ian Dardani(University of Pennsylvania), Benjamin Emert(University of Pennsylvania), Nicholas Bodkin(Northwestern University), Jonas Braun(Northwestern University), Dylan Fingerman(The Wistar Institute), Amanpreet Kaur(University of Pennsylvania), Naveen Jain(University of Pennsylvania), Pavithran T. Ravindran(University of Pennsylvania), Ian A. Mellis(University of Pennsylvania), Karun Kiani(University of Pennsylvania), Gretchen M. Alicea(Johns Hopkins University), Mitchell E. Fane(Johns Hopkins University), S. Ahmed(Northwestern University), Haiyin Li(The Wistar Institute), Yeqing Chen(The Wistar Institute), Cedric Chai(Northwestern University), Jessica Kaster(The Wistar Institute), Russell G. Witt(The University of Texas MD Anderson Cancer Center), Rossana Lazcano(The University of Texas MD Anderson Cancer Center), Davis R. Ingram(The University of Texas MD Anderson Cancer Center), Sarah B. Johnson(The University of Texas MD Anderson Cancer Center), Khalida Wani(The University of Texas MD Anderson Cancer Center), Margaret C. Dunagin(University of Pennsylvania), Alexander J. Lazar(The University of Texas MD Anderson Cancer Center), Ashani T. Weeraratna(Johns Hopkins University), Jennifer A. Wargo(The University of Texas MD Anderson Cancer Center), Meenhard Herlyn(The Wistar Institute), Arjun Raj(University of Pennsylvania)

Nature

July 19, 2023

10.1038/s41586-023-06342-8

Cited by 177Open Access

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