Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma

Xiao Chen(Institute of Physics), Chao Lü(Columbia University Irving Medical Center)

Nature Communications

July 17, 2023

10.1038/s41467-023-39990-5

Cited by 18

Related Papers

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

|Cancer Cell|2010|2.7k

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

|Cell|2022|216

Induction of sarcomas by mutant IDH2

|Genes & Development|2013|161

Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch

|Science Advances|2024|22

Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors

|Cell Reports|2023|20