High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization
Shu Feng(South China Normal University), Chongyun Wu(South China Normal University), Peibin Zou(South China Normal University), Qianting Deng(South China Normal University), Zhe Chen(South China Normal University), Meng Li(South China Normal University), Ling Zhu(South China Normal University), Fanghui Li(Nanjing Normal University), Timon Cheng‐Yi Liu(South China Normal University), Rui Duan(South China Normal University), Luodan Yang(South China Normal University)
Cited by 138Open Access
Abstract
Our findings indicate that HIIT ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype and astrocyte phenotype-associated AQP4 polarization. These changes promote Aβ and p-tau clearance from the brain tissue through the glymphatic system and the kidney.
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