Integration of microbial and chemical synthesis for the efficient production of plitidepsin, a promising anticancer and antiviral agent

Haili Zhang(Shenzhen Bay Laboratory), Xiaoyu Tang(South China Agricultural University), Minghao Sui(China Pharmaceutical University), Mengdi Liang(Anhui University of Science and Technology), Qiliang Lai(Fujian Institute of Oceanography), Zongze Shao(Ministry of Natural Resources), Jie Shen(Xinjiang Medical University), Lin Yang(Fujian Medical University), Min Zheng(Nanchang Hangkong University), Zhen Hui(Shenzhen Bay Laboratory), Shipeng Huang(Research Institute of Petroleum Exploration and Development), Xuyang Li(Shenzhen Bay Laboratory), Jie Dou(China Three Gorges University), Yun Ge(Shenzhen Bay Laboratory), Wenguang Shi(Shenzhen Bay Laboratory), Mingwei Cai(Chinese Academy of Sciences), Xiaozhou Luo(State Key Laboratory of Synthetic Chemistry)
bioRxiv (Cold Spring Harbor Laboratory)
April 24, 2023
Cited by 2


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