<scp>NanoBiT</scp>‐ and <scp>NanoBiT/BRET</scp>‐based assays allow the analysis of binding kinetics of Wnt‐3a to endogenous <scp>Frizzled 7</scp> in a colorectal cancer model
Lukas Grätz(Karolinska Institutet), Paweł Kozielewicz(Karolinska Institutet)
Cited by 10
Related Papers
Structural insight into small molecule action on Frizzleds
|Nature Communications|2020|85
Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments
|ACS Pharmacology & Translational Science|2021|42
A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine
|Molecular Pharmacology|2019|31
Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations
|Nature Communications|2023|25
SAG1.3-derived Frizzled-targeting small-molecule compounds
|Journal of Biological Chemistry|2025|2