Multi-ancestry genome-wide study in &gt;2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

Ken Suzuki; Soo‐Heon Kwak; Mart Kals; Alicia Huerta‐Chagoya; Yasuharu Tabara; Esteban J. Parra; Lauren E. Petty; Guðmar Þorleifsson; Fiona Bragg; Matthias Wuttke; Philip Schroeder; Xianyong Yin; Tamar Sofer; Darryl Nousome; Ozvan Bocher; Brett Vanderwerff; Shinichi Namba; Masahiro Nakatochi; Jung‐Jin Lee; Konstantinos Hatzikotoulas; Soumasree De; Mariaelisa Graff; Ian Pan; Henry J. Taylor; Jin Fang Chai; Lorraine Southam; Niels Grarup; Amel Lamri; Fumihiko Takeuchi; Daniel Taliun; Michael Preuß; Lawrence F. Bielak; Yang Hai; Kim Lorenz; James P. Cook; Christian Gieger; Chloé Sarnowski; Sanghoon Moon; Xiuqing Guo; Jana Nano; Stella Trompet; Ravi Mandla; Kyuto Sonehara; Jie Yao; Weihua Zhang; Young Jin Kim; Kuang Lin; Nigel W. Rayner; Robert A. Scott; Simon Lee

doi:10.1101/2023.03.31.23287839

Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

Ken Suzuki(The University of Osaka), Soo‐Heon Kwak(Seoul National University Hospital), Mart Kals(University of Tartu), Alicia Huerta‐Chagoya(Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán), Yasuharu Tabara(Kyushu University), Esteban J. Parra(University of Toronto), Lauren E. Petty(Vanderbilt University Medical Center), Guðmar Þorleifsson(deCODE Genetics (Iceland)), Fiona Bragg(University of Oxford), Matthias Wuttke(University of Freiburg), Philip Schroeder(Broad Institute), Xianyong Yin(University of Michigan), Tamar Sofer(Cardiovascular Institute Hospital), Darryl Nousome(University of Southern California), Ozvan Bocher(Helmholtz Zentrum München), Brett Vanderwerff(University of Michigan), Shinichi Namba(The University of Osaka), Masahiro Nakatochi(Nagoya University), Jung‐Jin Lee(Translational Therapeutics (United States)), Konstantinos Hatzikotoulas(Helmholtz Zentrum München), Soumasree De(Helmholtz Munich), Mariaelisa Graff(University of North Carolina at Chapel Hill), Ian Pan(Brown University), Henry J. Taylor(National Institutes of Health), Jin Fang Chai(National University of Singapore), Lorraine Southam(Essen University Hospital), Niels Grarup(University of Copenhagen), Amel Lamri(McMaster University), Fumihiko Takeuchi(National Center for Global Health and Medicine), Daniel Taliun(University of Michigan), Michael Preuß(University of Ottawa), Lawrence F. Bielak(University of Michigan), Yang Hai(The Lundquist Institute), Kim Lorenz(Translational Therapeutics (United States)), James P. Cook(University of Liverpool), Christian Gieger(Helmholtz Zentrum München), Chloé Sarnowski(Boston University), Sanghoon Moon(Korea National Institute of Health), Xiuqing Guo(UCLA Medical Center), Jana Nano(TUM Klinikum), Stella Trompet, Ravi Mandla(Broad Institute), Kyuto Sonehara(The University of Tokyo), Jie Yao(UCLA Medical Center), Weihua Zhang(Harbin Medical University), Young Jin Kim(Korea National Institute of Health), Kuang Lin(University of Oxford), Nigel W. Rayner(Centre for Human Genetics), Robert A. Scott(The Edgbaston Hospital), Simon Lee(Icahn School of Medicine at Mount Sinai)

medRxiv

March 31, 2023

10.1101/2023.03.31.23287839

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