Supplementary Figure S4: Western blot analysis of MAPK pathway inhibition by BI 847325 in KRAS-mutant cell lines. from Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases
Patrizia Sini, Ulrich Gürtler, Stephan K. Zahn, C. Baumann, Dorothea Rudolph, Rosa Baumgartinger, Eva Strauss, Christian Haslinger, Ulrike Tontsch-Grunt, Irene C. Waizenegger, Flavio Solca, Gerd Bader, Andreas Zoephel, Matthias Treu, Ulrich Reiser, Pilar Garin‐Chesa, Guido Boehmelt, Norbert Kraut, Jens Quant, Günther R. Adolf
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Abstract
<p>(A), MEK1 and phospho-MEK1/2; (B) ERK1/2 and phospho-ERK1/2.</p>
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