Heparan sulfate promotes ACE2 super-cluster assembly to enhance SARS-CoV-2-associated syncytium formation

Qi Zhang(Northeast Agricultural University), Yihong Ye(National Institute of Diabetes and Digestive and Kidney Diseases), Wei Zheng(Liaoning Cancer Hospital & Institute), Wenwei Huang(National Institutes of Health), Zulfeqhar A. Syed(National Institutes of Health), Layla Saidi(National Institutes of Health), Ivan Pavlinov(National Institutes of Health), Hang Xie(Nanjing University of Chinese Medicine), Eduardo Stancanelli(NewGen Therapeutics (United States)), Jian Liu(University of North Carolina at Chapel Hill), Bing Li(Wuhan University), Miao Xu(National Institutes of Health), Liqiang Chen(University of Minnesota), Peng Gao(Army Medical University), Wei‐Chun Tang(Center for Biologics Evaluation and Research), Catherine Z. Chen(National Institutes of Health), Eun-Kyung Jung(University of Minnesota), Vijayakanth Pagadala(Cotton (United States))
Research Square
March 28, 2023
10.21203/rs.3.rs-2693563/v1
Cited by 0

Related Papers

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium
|Cell stem cell|2020|460
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia
|Cancer Cell|2015|348
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
|Emerging Microbes & Infections|2014|242
Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening
|ACS Pharmacology & Translational Science|2020|225
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry
|Cell Discovery|2018|194