YTHDC2-mediated m6A mRNA modification of Id3 suppresses cisplatin resistance in non-small cell lung cancer

Xifan Wang(Nanjing University), Yu’an Hu(Nanjing General Hospital of Nanjing Military Command), Xiaoqing Li(Nanjing Traditional Chinese Medicine Hospital), Chuandong Zhu(Nanjing University of Chinese Medicine), Fangfang Chen(Jinling Institute of Technology)
Journal of Thoracic Disease
March 1, 2023
Cited by 14Open Access
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Abstract

Background: in controlling cisplatin resistance in non-small cell lung cancer (NSCLC). Methods: was clarified by m6A-immunoprecipitation-PCR (m6A-IP-PCR) assay. Results: mRNA. Conclusions: requires modifications to m6A, which ultimately inhibit cisplatin resistance in NSCLC.


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