Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

Adrian Gottschlich; Moritz Thomas; Ruth Grünmeier; Stefanie Lesch; Lisa Rohrbacher; Veronika Igl; Daria Briukhovetska; Mohamed-Reda Benmebarek; Binje Vick; Sertac Dede; K. Müller; Tao Xu; Dario Dhoqina; Florian Märkl; Sophie Robinson; Andrea Sendelhofert; Heiko Schulz; Öykü Umut; Vladyslav Kavaka; Christina Angeliki Tsiverioti; Emanuele Carlini; Sayantan Nandi; Thaddäus Strzalkowski; Theo Lorenzini; Sophia Stock; Philipp Jie Müller; Janina Dörr; Matthias Seifert; Bruno L. Cadilha; Ruben Brabenec; Natalie Röder; Felicitas Rataj; Manuel Nüesch; Franziska Modemann; Jasmin Wellbrock; Walter Fiedler; Christian Kellner; Eduardo Beltrán; Tobias Herold; Dominik Paquet; Irmela Jeremias; Louisa von Baumgarten; Stefan Endres; Marion Subklewe; Carsten Marr; Sebastian Kobold

doi:10.1038/s41587-023-01684-0

Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

Adrian Gottschlich(LMU Klinikum), Moritz Thomas(Helmholtz Zentrum München), Ruth Grünmeier(German Center for Lung Research), Stefanie Lesch(German Center for Lung Research), Lisa Rohrbacher(LMU Klinikum), Veronika Igl(German Center for Lung Research), Daria Briukhovetska(German Center for Lung Research), Mohamed-Reda Benmebarek(German Center for Lung Research), Binje Vick(Helmholtz Zentrum München), Sertac Dede(LMU Klinikum), K. Müller(LMU Klinikum), Tao Xu(LMU Klinikum), Dario Dhoqina(German Center for Lung Research), Florian Märkl(German Center for Lung Research), Sophie Robinson(LMU Klinikum), Andrea Sendelhofert(LMU Klinikum), Heiko Schulz(LMU Klinikum), Öykü Umut(German Center for Lung Research), Vladyslav Kavaka(LMU Klinikum), Christina Angeliki Tsiverioti(German Center for Lung Research), Emanuele Carlini(German Center for Lung Research), Sayantan Nandi(German Center for Lung Research), Thaddäus Strzalkowski(German Center for Lung Research), Theo Lorenzini(German Center for Lung Research), Sophia Stock(LMU Klinikum), Philipp Jie Müller(German Center for Lung Research), Janina Dörr(German Center for Lung Research), Matthias Seifert(German Center for Lung Research), Bruno L. Cadilha(German Center for Lung Research), Ruben Brabenec(Helmholtz Zentrum München), Natalie Röder(German Center for Lung Research), Felicitas Rataj(German Center for Lung Research), Manuel Nüesch(German Center for Lung Research), Franziska Modemann(Universität Hamburg), Jasmin Wellbrock(Universität Hamburg), Walter Fiedler(Universität Hamburg), Christian Kellner(Ludwig-Maximilians-Universität München), Eduardo Beltrán(LMU Klinikum), Tobias Herold(LMU Klinikum), Dominik Paquet(LMU Klinikum), Irmela Jeremias(Helmholtz Zentrum München), Louisa von Baumgarten(LMU Klinikum), Stefan Endres(Helmholtz Zentrum München), Marion Subklewe(LMU Klinikum), Carsten Marr(Helmholtz Zentrum München), Sebastian Kobold(German Cancer Research Center)

Nature Biotechnology

March 13, 2023

10.1038/s41587-023-01684-0

Cited by 108Open Access

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