FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC
Xilang Chen, Jie Chen, Weibo Feng, Wenjie Huang(Tongji Hospital), Guodong Wang, Mengyu Sun(Tongji Hospital), Xiangyuan Luo(Tongji Hospital), Yijun Wang(Tongji Hospital), Yongzhan Nie, Daiming Fan, Kaichun Wu, Limin Xia(Tongji Hospital)
Cited by 36Open Access
Abstract
We demonstrated the essentiality of ELF4 in the metastatic process of CRC, and targeting the ELF4-relevant positive feedback circuit might represent a novel therapeutic strategy.
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