Application of Collagen-Based Hydrogel in Skin Wound Healing

Yuan Zhang(Sir Run Run Shaw Hospital), Yong Wang(Sir Run Run Shaw Hospital), Ying Li(Sir Run Run Shaw Hospital), Yunpeng Yang(Sir Run Run Shaw Hospital), Ming-Yuan Jin(Sir Run Run Shaw Hospital), Xiaoying Lin(Sir Run Run Shaw Hospital), Z. Zhuang(Sir Run Run Shaw Hospital), Kai Guo(Sir Run Run Shaw Hospital), Tao Zhang(Sir Run Run Shaw Hospital), Wei‐Qiang Tan(Sir Run Run Shaw Hospital)
Gels
February 27, 2023
Cited by 138Open Access
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Abstract

The repair of skin injury has always been a concern in the medical field. As a kind of biopolymer material with a special network structure and function, collagen-based hydrogel has been widely used in the field of skin injury repair. In this paper, the current research and application status of primal hydrogels in the field of skin repair in recent years are comprehensively reviewed. Starting from the structure and properties of collagen, the preparation, structural properties, and application of collagen-based hydrogels in skin injury repair are emphatically described. Meanwhile, the influences of collagen types, preparation methods, and crosslinking methods on the structural properties of hydrogels are emphatically discussed. The future and development of collagen-based hydrogels are prospected, which is expected to provide reference for the research and application of collagen-based hydrogels for skin repair in the future.


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