Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022
Montserrat Agüero(Ministerio de Agricultura, Pesca y Alimentación), Isabella Monne(Istituto Zooprofilattico Sperimentale delle Venezie), Azucena Sánchez(Ministerio de Agricultura, Pesca y Alimentación), Bianca Zecchin(Istituto Zooprofilattico Sperimentale delle Venezie), Alice Fusaro(Istituto Zooprofilattico Sperimentale delle Venezie), Marı́a José Ruano(Ministerio de Agricultura, Pesca y Alimentación), Manuel del Valle Arrojo(Xunta de Galicia), Ricardo Fernández-Antonio(Gerontologic Complex La Milagrosa), Antonio Manuel Souto(Xunta de Galicia), Pedro Tordable(Xunta de Galicia), Julio Cañás(Xunta de Galicia), Francesco Bonfante(Istituto Zooprofilattico Sperimentale delle Venezie), Edoardo Giussani(Istituto Zooprofilattico Sperimentale delle Venezie), Calogero Terregino(Istituto Zooprofilattico Sperimentale delle Venezie), Jesús Javier Orejas(Xunta de Galicia)
Cited by 385Open Access
Abstract
In October 2022, an outbreak in Europe of highly pathogenic avian influenza (HPAI) A(H5N1) in intensively farmed minks occurred in northwest Spain. A single mink farm hosting more than 50,000 minks was involved. The identified viruses belong to clade 2.3.4.4b, which is responsible of the ongoing epizootic in Europe. An uncommon mutation (T271A) in the PB2 gene with potential public health implications was found. Our investigations indicate onward mink transmission of the virus may have occurred in the affected farm.
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