Re-evaluating the need for chronic toxicity studies with therapeutic monoclonal antibodies, using a weight of evidence approach
Hsiao-Tzu Chien(Radboud University Nijmegen), Peter van Meer(Medicines Evaluation Board), Michael W. Leach(Pfizer (United States)), Helen Prior(National Centre for the Replacement Refinement and Reduction of Animals in Research), Maggie Dempster(GlaxoSmithKline (United States)), Katrin Schütte(European Commission), Noël Dybdal, Adam Hey(AstraZeneca (United Kingdom)), Wendy Freebern(Bristol-Myers Squibb (Germany)), Leon van Aerts(Medicines Evaluation Board), Thomas Kissner(Sanofi (Germany)), Lolke de Haan(AstraZeneca (United Kingdom)), Annick Cauvin(UCB Pharma (Belgium)), Kaushik Datta(Bristol-Myers Squibb (Germany)), Lucinda Weir(GlaxoSmithKline (United Kingdom)), Donna Lee, Fiona Sewell(National Centre for the Replacement Refinement and Reduction of Animals in Research), David O. Clarke(Eli Lilly (United States)), Laura Andrews, Sven Kronenberg(Roche (Switzerland)), Peter Ulrich(University of Potsdam), Kevin Trouba(Janssen (United States))
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