Reconsideration of Antinucleocapsid IgG Antibody as a Marker of SARS-CoV-2 Infection Postvaccination for Mild COVID-19 Patients
Santosh Dhakal(Johns Hopkins University), Tong Yu(Johns Hopkins University), Anna Yin(Johns Hopkins University), Nora Pisanic(Johns Hopkins University), Zoe O Demko(Johns Hopkins University), Annukka A.R. Antar(Johns Hopkins University), Andrea L. Cox(Johns Hopkins University), Christopher D. Heaney(Johns Hopkins University), Yukari C. Manabe(Johns Hopkins University), Sabra L. Klein(Johns Hopkins University)
Cited by 51Open Access
Abstract
Antinucleocapsid (anti-N) immunoglobulin G antibody responses were lower in plasma and oral fluid after severe acute respiratory syndrome coronavirus 2 infection in vaccinated patients compared with patients infected before vaccination or infected without vaccination. This raises questions about the long-term use of anti-N antibodies as a marker for natural infection for surveillance.
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