Early detection and prognosis prediction for colorectal cancer by circulating tumour DNA methylation haplotypes: a multicentre cohort study
Shaobo Mo(Shanghai Medical College of Fudan University), Weixing Dai(Shanghai Medical College of Fudan University), Hui Wang(Sinotech Genomics (China)), Xiao-Liang Lan(Nanfang Hospital), Chengcheng Ma(Sinotech Genomics (China)), Zhixi Su(Sinotech Genomics (China)), Wenqiang Xiang(Shanghai Medical College of Fudan University), Lingyu Han(Shanghai Medical College of Fudan University), Wenqin Luo(Shanghai Medical College of Fudan University), Long Zhang(Shanghai Medical College of Fudan University), Renjie Wang(Shanghai Medical College of Fudan University), Yaodong Zhang(Fudan University Shanghai Cancer Center), Wenming Zhang(Fudan University Shanghai Cancer Center), Lin Yang(Fudan University Shanghai Cancer Center), Renquan Lu(Fudan University Shanghai Cancer Center), Lin Guo(Fudan University Shanghai Cancer Center), Ying Zheng(Fudan University Shanghai Cancer Center), Mingzhu Huang(Fudan University Shanghai Cancer Center), Ye Xu(Shanghai Medical College of Fudan University), Liang Li(Nanfang Hospital), Sanjun Cai(Shanghai Medical College of Fudan University), Guo‐Xiang Cai(Shanghai Medical College of Fudan University)
Cited by 83Open Access
Abstract
Background Early detection and prognosis prediction of colorectal cancer (CRC) can significantly reduce CRC-related mortality. Recently, circulating tumour DNA (ctDNA) methylation has shown good application foreground in the early detection and prognosis prediction of multiple tumours.
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