Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis

Le Qin(Shanghai Jiao Tong University), Peng Li(Chinese Academy of Sciences), Jie Yang(South China Normal University), Pentao Liu(Hong Kong Science and Technology Parks Corporation), Yuanbin Cui(Chinese Academy of Sciences), Tingjie Yuan(Guangzhou Medical University), Huixia Pan(Shenzhen Luohu People's Hospital), Jean Paul Thiery(Centre National de la Recherche Scientifique), Dajiang Qin(Second Affiliated Hospital of Guangzhou Medical University), Youguo Long(Chinese Academy of Sciences), Qiting Wu(Chinese Academy of Sciences), Zhaoyang Tang(Academy of Medical Sciences), Ruocong Zhao(Chinese Academy of Sciences), Zhiwu Jiang(Guangxi University), Wei Wei(Institute of Process Engineering), Yao Yao(Dalian Medical University), Xiaoping Li(Sun Yat-sen University), Dongmei Chen(The University of Texas at Austin), Zhenfeng Zhang(Dalian Medical University), Shanglin Li(Tsinghua University), Suna Wang(National Institutes of Health), Robert Weinkove(Malaghan Institute of Medical Research), Qiannan Tang(University of Oxford), Xue‐Qun Luo(Sun Yat-sen University)
Nature Communications
October 13, 2022
Cited by 46


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