The Intratumoral Bacterial Metataxonomic Signature of Hepatocellular Carcinoma
Jian-Hang Huang(Fudan University), Jie Wang(Fudan University), Xiaoqiang Chai(Fudan University), Zhong-Chen Li(Fudan University), Ying-Hua Jiang(Fudan University), Jun Li(Tongren Hospital), Xing Liu(Shanghai University of Traditional Chinese Medicine), Jia Fan(Fudan University), Jiabin Cai(Fudan University), Feng Liu(Fudan University)
Cited by 92Open Access
Abstract
Gut microbiome is an important regulator of hepatic inflammation, detoxification, and immunity, and contributes to the carcinogenesis of liver cancer. Intratumoral bacteria are supposed to be closer to the tumor cells, forming a microenvironment that may be relevant to the pathological process of hepatocellular carcinoma (HCC).
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