A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Kyriaki Michailidou(Cyprus Institute of Neurology and Genetics), Adam S. Butterworth(University of Cambridge), Michael Boehnke(University of Michigan), J. Wouter Jukema(Leiden University Medical Center), Dawn Waterworth(GlaxoSmithKline (United States)), Jukka Kontto(Finnish Institute for Health and Welfare), Deborah J. Thompson, Rosalind A. Eeles(Royal Marsden NHS Foundation Trust), Stephen O’Rahilly(Wellcome/MRC Institute of Metabolic Science), Jean Ferrières(Université Fédérale de Toulouse Midi-Pyrénées), Patricia B. Munroe(Queen Mary University of London), James S. Pankow(University of Minnesota System), Jian’an Luan(University of Cambridge), Janet Dunn(National Health Service), Thomas Foltynie(National Hospital for Neurology and Neurosurgery), Philippe Amouyel(Inserm), John Danesh(University of Cambridge), Martina Müller‐Nurasyid(Helmholtz Zentrum München), Jette Bork‐Jensen(University of Copenhagen), Kari Kuulasmaa(Finnish Institute for Health and Welfare), Carlos Cruchaga(Washington University in St. Louis), Rebecca Sims(Amsterdam Neuroscience), Frank Kee(Queen's University Belfast), Eric Boerwinkle(Training Programs in Epidemiology and Public Health Interventions Network), Jaspal S. Kooner(Imperial College Healthcare NHS Trust), Daphne L. van der A(National Institute for Public Health and the Environment), Ali Amin Al Olama(Institute of Cancer Research), Heiner Boeing(German Institute of Human Nutrition), Yvonne T. van der Schouw(University Medical Center Utrecht), L. Adrienne Cupples(Boston University), Timothy J. Key(University of Oxford), Beverley Balkau(Inserm), Nita G. Forouhi(University of Cambridge), Oluf Pedersen(University of Copenhagen), Nisa M. Maruthur(Johns Hopkins University), Sara Benlloch Garcia(University of Cambridge), Margaret G. Ehm(GlaxoSmithKline (United States)), Naveed Sattar(University of Glasgow), Robin Young(University of Glasgow), Jennifer L. Aponte, Helena Earl(University of Cambridge), Stella Trompet, Mark Walker(Children's Hospital of Eastern Ontario), Carlos A. González(Bellvitge University Hospital), Péter Vollenweider(University of Lausanne), Christopher Poole(Guy's Hospital), Audrey Y. Chu(University of Helsinki), Torben Jørgensen(University of Copenhagen), Aldi T. Kraja, Chris J. Packard(University of Glasgow)
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