S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer

Hongnan Mo(Chinese Academy of Medical Sciences & Peking Union Medical College), Fei Ma(Chinese Academy of Medical Sciences & Peking Union Medical College), Yu Xue(Dalian Medical University), Jiashu Han(IIT@MIT), Zhangfu Li(Chinese Academy of Medical Sciences & Peking Union Medical College), Caiming Li(Chinese Academy of Sciences), Yongmei Song(Hebei Medical University), Shuang Wang(Dalian Medical University), Hongyan Chen(Chinese Academy of Medical Sciences & Peking Union Medical College), Dan Li(Harbin University of Commerce), Xuefeng Liu(Dalian Medical University), Ming Fu(Chinese Academy of Medical Sciences & Peking Union Medical College), Shichao Guo(Chinese Academy of Medical Sciences & Peking Union Medical College)
Molecular Cancer
August 30, 2022
10.1186/s12943-022-01642-5
Cited by 57

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