High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Brian R. Shy(Gladstone Institutes), Vivasvan S. Vykunta(Gladstone Institutes), Alvin Ha(Gladstone Institutes), Alexis Talbot(Gladstone Institutes), Theodore L. Roth(Gladstone Institutes), David N. Nguyen(Gladstone Institutes), Wolfgang Pfeifer(The Ohio State University), Yan Yi Chen(Gladstone Institutes), Franziska Blaeschke(Gladstone Institutes), Eric Shifrut(Gladstone Institutes), Shane Vedova(Gladstone Institutes), Murad R. Mamedov(Gladstone Institutes), Jing-Yi Chung(Gladstone Institutes), Hong Li, Ruby Yu(Gladstone Institutes), David Wu(University of California, San Francisco), Jeffrey L. Wolf(University of California, San Francisco), Thomas Martin(University of California, San Francisco), Carlos E. Castro(The Ohio State University), Lumeng Ye, Jonathan H. Esensten(Gladstone Institutes), Justin Eyquem(Gladstone Institutes), Alexander Marson(Gladstone Institutes)
Nature Biotechnology
August 25, 2022
10.1038/s41587-022-01418-8
Cited by 218Open Access
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