CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of <i>C9orf72</i> poly(PR) toxicity

Wenting Guo(Hubei Polytechnic University), Catherine M. Verfaillie(KU Leuven), Philip Van Damme(Universitair Ziekenhuis Leuven), Tine Tricot(KU Leuven), Sriram Balusu(Ghent University), Bart De Strooper(VIB-KU Leuven Center for Brain & Disease Research), Dietmar Rudolf Thal(Allen Institute for Brain Science), Madhavsai Gajjar(Rega Institute for Medical Research), Arun Kumar Tharkeshwar(IMEC), Nicole Hersmus(VIB-KU Leuven Center for Brain & Disease Research), Francis Impens(Ghent University), Pieter Vanden Berghe(KU Leuven), Julien Couthouis(Stanford University), Rekin’s Janky(KU Leuven), Siddharthan Chandran(Edinburgh Royal Infirmary), Maarten Jacquemyn(Rega Institute for Medical Research), Ritchie Ho(Cedars-Sinai Medical Center), Muralidhar L. Hegde(Houston Methodist), Ludo Van Den Bosch(VIB-KU Leuven Center for Brain & Disease Research), Rik Vandenberghe(Allen Institute for Brain Science), Laura Fumagalli(VIB-KU Leuven Center for Brain & Disease Research), Dirk Daelemans(Rega Institute for Medical Research), Elke Braems(VIB-KU Leuven Center for Brain & Disease Research), Pegah Masrori(Valve (United States)), Evelien Van Schoor(VIB-KU Leuven Center for Brain & Disease Research), Haibo Wang(The Third People's Hospital of Dalian City), Rodrigo Madeiro da Costa(Rega Institute for Medical Research), Karan Ahuja(KU Leuven), Yannan Fan(Rega Institute for Medical Research), Matthieu Moisse(VIB-KU Leuven Center for Brain & Disease Research)

Alzheimer s & Dementia

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