A Randomised Trial of Ultrasonographic Assessment of Gastric Emptying Following Water Ingestion in Healthy Volunteers

William Headdon(Southmead Hospital), Ben Ballisat(Southmead Hospital), Christopher C. Thompson(Southmead Hospital), Peter Klepsch(Southmead Hospital), Sam Leary(University Hospitals Bristol NHS Foundation Trust), Linda Hunt(University Hospitals Bristol NHS Foundation Trust), Andy Ness(University Hospitals Bristol NHS Foundation Trust), Charlotte Atkinson(University Hospitals Bristol NHS Foundation Trust)
Research Square
July 26, 2022
Cited by 0Open Access
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Abstract

Abstract Background: Current guidance on pre-operative fasting for clear fluids to reduce aspiration risk may result in unnecessary dehydration and more liberal fluid regimes are being advocated. Methods: This randomised single blinded crossover study used an established ultrasound protocol to measure the gastric volume of 15 healthy volunteers following the 2011 European Society of Anaesthesia (ESA) ‘Perioperative Fasting in Adults and Children’ guidelines (nil-by-mouth two hours before induction of anaesthesia) and the 2005 Scandinavian guidelines (150 mL water with medication up to 1 hour before induction of anaesthesia). Results: We observed that gastric volumes increased following ingestion of water in all individuals compared to their fasted states. Water left the stomach within 30 minutes following ingestion in ten individuals, and within an hour in three individuals (gastric volume < 1.5 ml kg − 1 ). A reduction in thirst was observed in the group allowed to drink water, whereas hunger and anxiety scores were unaffected.


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