The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms
Rita Alaggio(Bambino Gesù Children's Hospital), Catalina Amador(University of Miami), Ioannis Anagnostopoulos(University of Würzburg), Ayoma D. Attygalle(Royal Marsden Hospital), Iguaracyra Araújo(Universidade Federal da Bahia), Emilio Berti(University of Milan), Govind Bhagat(Columbia University Irving Medical Center), Anita Borges(S.L. Raheja Hospital), Daniel F. Boyer(University of Michigan), Maria Calaminici(Barts Health NHS Trust), Amy Chadburn(Cornell University), John K. C. Chan(Queen Elizabeth Hospital), Wah Cheuk(Queen Elizabeth Hospital), Wee Joo Chng(National University Cancer Institute, Singapore), John Choi(University of Alabama at Birmingham), Shih‐Sung Chuang(Chi Mei Medical Center), Sarah E. Coupland, Magdalena Czader(Indiana University – Purdue University Indianapolis), Sandeep S. Davé(Duke University), Daphne de Jong(Amsterdam University Medical Centers), Ming‐Qing Du(MRC Laboratory of Molecular Biology), Kojo S.J. Elenitoba‐Johnson(University of Pennsylvania), Judith A. Ferry(Harvard University), Julia T. Geyer(Cornell University), Dita Gratzinger(Stanford University), Joan Guitart(Northwestern University), Sumeet Gujral(Tata Memorial Hospital), Marian H. Harris(Boston Children's Hospital), Christine J. Harrison(Newcastle University), Sylvia Hartmann(Goethe University Frankfurt), Andreas Hochhaus(Jena University Hospital), Patty M. Jansen(Leiden University Medical Center), Kennosuke Karube, Werner Kempf, Joseph D. Khoury(The University of Texas MD Anderson Cancer Center), Hiroshi Kimura(Nagoya University), Wolfgang Hiddemann(University Hospital Schleswig-Holstein), Alexandra E. Kovach(Children's Hospital of Los Angeles), Shaji Kumar(Mayo Clinic in Arizona), Alexander J. Lazar(The University of Texas MD Anderson Cancer Center), Stefano Lazzi(University of Siena), Lorenzo Leoncini(University of Siena), Nelson Leung(Mayo Clinic in Arizona), Vasiliki Leventaki(Children's Hospital of Wisconsin), Xiao‐Qiu Li(Fudan University Shanghai Cancer Center), Megan S. Lim(University of Pennsylvania), Weiping Liu(Sichuan University), Abner Louissaint(Harvard University), Andrea N. Marcogliese(Baylor College of Medicine), L. Jeffrey Medeiros(The University of Texas MD Anderson Cancer Center), Michael Michal(Charles University), Roberto N. Miranda(The University of Texas MD Anderson Cancer Center), Christina Mitteldorf(Universitätsmedizin Göttingen), Santiago Montes‐Moreno(Marqués de Valdecilla University Hospital), William G. Morice(Mayo Clinic in Arizona), Valentina Nardi(Harvard University), Kikkeri N. Naresh(Fred Hutch Cancer Center), Yasodha Natkunam(Stanford University), Siok‐Bian Ng(National University of Singapore), Ilske Oschlies(University Hospital Schleswig-Holstein), German Ott(Robert Bosch Hospital), Marie Parrens(Université de Bordeaux), Melissa Pulitzer(Memorial Sloan Kettering Cancer Center), S. Vincent Rajkumar(Mayo Clinic), Andy C. Rawstron(Leeds Teaching Hospitals NHS Trust), Karen L. Rech(Mayo Clinic in Arizona), Andreas Rosenwald(University of Würzburg), Jonathan Said(University of California, Los Angeles), Clémentine Sarkozy(Institut Gustave Roussy), Shahin Sayed(Aga Khan University Hospital Nairobi), Caner Saygin(University of Chicago), Anna Schuh(University of Oxford), William A. Sewell(Garvan Institute of Medical Research), Reiner Siebert(Universität Ulm), Aliyah R. Sohani(Harvard University), Reuben Tooze(University of Leeds), Alexandra Traverse‐Glehen(Université Claude Bernard Lyon 1), Francisco Vega(The University of Texas MD Anderson Cancer Center), B. Vergier(Hôpital Cardiologique du Haut-Lévêque), Ashutosh Wechalekar(University College London), Brent L. Wood(Children's Hospital of Los Angeles), Luc Xerri(Institut Paoli-Calmettes), Wenbin Xiao(Memorial Sloan Kettering Cancer Center)
Cited by 3,657Open Access
Abstract
Abstract We herein present an overview of the upcoming 5 th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4 th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5 th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.
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