A catalog of 48,425 nonredundant viruses from oral metagenomes expands the horizon of the human oral virome

Shenghui Li(Dalian Medical University), Ruochun Guo, Yue Zhang, Peng Li, Fang Chen(Dalian Medical University), Xifan Wang(China Agricultural University), Jing Li(Peking University), Zhuye Jie(University of Copenhagen), Qingbo Lv, Hao Jin(Inner Mongolia Agricultural University), Guangyang Wang(Dalian Medical University), Qiulong Yan(Dalian Medical University)
iScience
May 18, 2022
Cited by 78Open Access
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Abstract

phages and jumbo viruses. Comparisons of the viral diversity and abundance of different oral cavity habitats suggested strong niche specialization of viromes within individuals. The virome variations in relation to host geography and properties were further uncovered, especially the age-dependent viral compositional signatures in saliva. Overall, the viral genome catalog describes the architecture and variability of the human oral virome, while offering new resources and insights for current and future studies.


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