Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Julia A. Belk(Stanford University), Ansuman T. Satpathy(Palo Alto University), Quanming Shi(Stanford University), Connor V. Duffy(Stanford University), Julia Carnevale(Gladstone Institutes), Santosha A. Vardhana(Memorial Sloan Kettering Cancer Center), Katherine A. Freitas(Stanford University), Madeline A. Hwee(Memorial Sloan Kettering Cancer Center), Alan Ashworth(University of California, San Francisco), Eric Shifrut(Gladstone Institutes), Alfredo M. Valencia(Broad Institute), Nghi Ly(Stanford University), Alexander Marson(Gladstone Institutes), Kathryn E. Yost(Whitehead Institute for Biomedical Research), Crystal L. Mackall(Parker Institute for Cancer Immunotherapy), Zhuang Miao(Stanford University), Nupura Kale(University of California, San Francisco), Yanting Chen(Memorial Sloan Kettering Cancer Center), Winnie Yao(Stanford University)
bioRxiv (Cold Spring Harbor Laboratory)
April 21, 2022
Cited by 36


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