Database resources of the National Center for Biotechnology Information

Eric W Sayers(National Institutes of Health), Jeffrey Beck(National Institutes of Health), Evan Bolton(National Institutes of Health), Devon Bourexis(National Institutes of Health), J. Rodney Brister(National Institutes of Health), Kathi Canese(National Institutes of Health), Donald C. Comeau(National Institutes of Health), Kathryn Funk(National Institutes of Health), Sunghwan Kim(National Institutes of Health), William Klimke(National Institutes of Health), Aron Marchler‐Bauer(National Institutes of Health), Melissa Landrum(National Institutes of Health), Stacy Lathrop(National Institutes of Health), Zhiyong Lu(National Institutes of Health), Thomas Madden(National Institutes of Health), Nuala A. O’Leary(National Institutes of Health), Lon Phan(National Institutes of Health), Sanjida H Rangwala(National Institutes of Health), Valérie Schneider(National Institutes of Health), Yuri Skripchenko(National Institutes of Health), Jiyao Wang(National Institutes of Health), Jian Ye(National Institutes of Health), Barton W Trawick(National Institutes of Health), Kim D. Pruitt(National Institutes of Health), Stephen T. Sherry(National Institutes of Health)
Nucleic Acids Research
October 8, 2020
10.1093/nar/gkaa892
Cited by 1,006Open Access
Full Text

Abstract

The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed® database of citations and abstracts published in life science journals. The Entrez system provides search and retrieval operations for most of these data from 34 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Custom implementations of the BLAST program provide sequence-based searching of many specialized datasets. New resources released in the past year include a new PubMed interface and NCBI datasets. Additional resources that were updated in the past year include PMC, Bookshelf, Genome Data Viewer, SRA, ClinVar, dbSNP, dbVar, Pathogen Detection, BLAST, Primer-BLAST, IgBLAST, iCn3D and PubChem. All of these resources can be accessed through the NCBI home page at https://www.ncbi.nlm.nih.gov.

Related Papers

BLAST+: architecture and applications
Christiam Camacho, George Coulouris, Vahram Avagyan et al.|BMC Bioinformatics|2009|23k
Database resources of the National Center for Biotechnology Information: update
David Wheeler|Nucleic Acids Research|2003|11k
NCBI prokaryotic genome annotation pipeline
Tatiana Tatusova, Michael DiCuccio, Azat Badretdin et al.|Nucleic Acids Research|2016|6.9k
Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction
Jian Ye, George Coulouris, Irena Zaretskaya et al.|BMC Bioinformatics|2012|6.2k
PubChem Substance and Compound databases
Sunghwan Kim, Paul Thiessen, Evan Bolton et al.|Nucleic Acids Research|2015|5.4k