Complete Genome Sequence of the Methanogenic Archaeon, <b> <i>Methanococcus jannaschii</i> </b>
Carol J. Bult(University of Illinois Urbana-Champaign), Owen White(University of Illinois Urbana-Champaign), Gary J. Olsen(University of Illinois Urbana-Champaign), Lixin Zhou(University of Illinois Urbana-Champaign), Robert Fleischmann(University of Illinois Urbana-Champaign), Granger G. Sutton(University of Illinois Urbana-Champaign), Judith A. Blake(University of Illinois Urbana-Champaign), Lisa M. Fitzgerald(University of Illinois Urbana-Champaign), Rebecca A. Clayton(University of Illinois Urbana-Champaign), Jeannine D. Gocayne(University of Illinois Urbana-Champaign), Anthony R. Kerlavage(University of Illinois Urbana-Champaign), Brian Dougherty(University of Illinois Urbana-Champaign), Jean-François Tomb(University of Illinois Urbana-Champaign), Mark D. Adams(University of Illinois Urbana-Champaign), Claudia I. Reich(University of Illinois Urbana-Champaign), Ross Overbeek(Argonne National Laboratory), Ewen F. Kirkness(University of Illinois Urbana-Champaign), Keith G. Weinstock(University of Illinois Urbana-Champaign), Joseph M. Merrick(University at Buffalo, State University of New York), Anna Glodek(University of Illinois Urbana-Champaign), John Scott(University of Illinois Urbana-Champaign), Neil S. Geoghagen(University of Illinois Urbana-Champaign), Janice F. Weidman(University of Illinois Urbana-Champaign), Joyce L. Fuhrmann(University of Illinois Urbana-Champaign), Dave Nguyen(University of Illinois Urbana-Champaign), Teresa R. Utterback(University of Illinois Urbana-Champaign), Jenny M. Kelley(University of Illinois Urbana-Champaign), Jeremy Peterson(University of Illinois Urbana-Champaign), Paul W. Sadow(University of Illinois Urbana-Champaign), Michael C. Hanna(University of Illinois Urbana-Champaign), Matthew Cotton(University of Illinois Urbana-Champaign), Kevin Roberts(University of Illinois Urbana-Champaign), Margaret A. Hurst(University of Illinois Urbana-Champaign), Brian P. Kaine(University of Illinois Urbana-Champaign), Mark Borodovsky(Georgia Institute of Technology), Hans‐Peter Klenk(University of Illinois Urbana-Champaign), Claire M. Fraser(University of Illinois Urbana-Champaign), Hamilton O. Smith(Johns Hopkins University), Carl R. Woese(University of Illinois Urbana-Champaign), J. Craig Venter(University of Illinois Urbana-Champaign)
Cited by 2,071
Abstract
The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of 1738 predicted protein-coding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence. Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are more similar to those found in Eukaryotes.