Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer’s-like Pathology in the Hippocampus by Altering the Phenotype of Microglia in APP/PS1 Mouse Model

Di Wu; Yafang Zhang; Xiaodi Lu; Xudong Tang; Liang Sun; Xin Liu; Bin Liu; Yixuan Li; Meitong Nie; Dongsheng Mao; Jay Prakash Prasad Kumal

doi:10.21203/rs.3.rs-92179/v1

Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer’s-like Pathology in the Hippocampus by Altering the Phenotype of Microglia in APP/PS1 Mouse Model

Di Wu(Harbin Medical University), Yafang Zhang(Xinzhou Teachers University), Xiaodi Lu(Harbin Medical University), Xudong Tang(Chinese Academy of Medical Sciences & Peking Union Medical College), Liang Sun(Capital Medical University), Xin Liu(Northern Hospital), Bin Liu(Harbin Medical University), Yixuan Li(Wuhan University), Meitong Nie(Ministry of Education of the People's Republic of China), Dongsheng Mao(Tongji University), Jay Prakash Prasad Kumal(Ministry of Education of the People's Republic of China)

Research Square

October 19, 2020

10.21203/rs.3.rs-92179/v1

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Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer’s-like Pathology in the Hippocampus by Altering the Phenotype of Microglia in APP/PS1 Mouse Model

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