Author response: Single-color, ratiometric biosensors for detecting signaling activities in live cells

Brian Ross(Johns Hopkins University), Brian Tenner(Johns Hopkins University), Michele L. Markwardt(University of Maryland, Baltimore), Adam Zviman(University of Maryland, Baltimore), Guoli Shi(University of Maryland, Baltimore), Jaclyn P. Kerr(University of Maryland, Baltimore), Nicole E. Snell(University of Maryland, Baltimore), Jennifer J McFarland(University of Maryland, Baltimore), Joseph R. H. Mauban(University of Maryland, Baltimore), Christopher W. Ward(University of Maryland, Baltimore), Megan A. Rizzo(University of Maryland, Baltimore), Jin Zhang(Johns Hopkins University)
Unknown
June 5, 2018
10.7554/elife.35458.sa2
Cited by 2Open Access
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Abstract

A novel panel of homoFRET biosensors that detect kinase and second messenger activity, called FLAREs, enables multiparameter imaging of signaling activities within a single live cell with a quantitative and ratiometric readout.

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