Ensembl 2015

Fiona Cunningham(European Bioinformatics Institute), M Ridwan Amode(European Bioinformatics Institute), Daniel Barrell(European Bioinformatics Institute), Kathryn Beal(European Bioinformatics Institute), Konstantinos Billis(European Bioinformatics Institute), Simon Brent(Wellcome Sanger Institute), Denise Carvalho‐Silva(European Bioinformatics Institute), Peter Clapham(Wellcome Sanger Institute), Guy Coates(Wellcome Sanger Institute), Stephen Fitzgerald(European Bioinformatics Institute), Laurent Gil(European Bioinformatics Institute), Carlos García Girón(European Bioinformatics Institute), Leo I. Gordon(European Bioinformatics Institute), Thibaut Hourlier(European Bioinformatics Institute), Sarah Hunt(European Bioinformatics Institute), Sophie H. Janacek(European Bioinformatics Institute), Nathan Johnson(European Bioinformatics Institute), Thomas Juettemann(European Bioinformatics Institute), Andreas Kähäri(Wellcome Sanger Institute), Stephen Keenan(European Bioinformatics Institute), Fergal J. Martin(European Bioinformatics Institute), Thomas Maurel(European Bioinformatics Institute), William McLaren(European Bioinformatics Institute), Daniel N. Murphy(European Bioinformatics Institute), Rishi Nag(European Bioinformatics Institute), Bert Overduin(European Bioinformatics Institute), Anne Parker(European Bioinformatics Institute), Mateus Patrício(European Bioinformatics Institute), Emily Perry(European Bioinformatics Institute), Miguel Pignatelli(European Bioinformatics Institute), Harpreet Singh Riat(European Bioinformatics Institute), Dan Sheppard(European Bioinformatics Institute), Kieron Taylor(European Bioinformatics Institute), Anja Thormann(European Bioinformatics Institute), Alessandro Vullo(European Bioinformatics Institute), Steven P. Wilder(European Bioinformatics Institute), Amonida Zadissa(European Bioinformatics Institute), Bronwen Aken(European Bioinformatics Institute), Ewan Birney(European Bioinformatics Institute), Jennifer Harrow(Wellcome Sanger Institute), Rhoda Kinsella(European Bioinformatics Institute), Matthieu Muffato(European Bioinformatics Institute), Magali Ruffier(European Bioinformatics Institute), Stephen M. J. Searle(Wellcome Sanger Institute), Giulietta Spudich(European Bioinformatics Institute), Stephen J. Trevanion(European Bioinformatics Institute), Andy Yates(European Bioinformatics Institute), Daniel R. Zerbino(European Bioinformatics Institute), Paul Flicek(European Bioinformatics Institute)
Nucleic Acids Research
October 28, 2014
10.1093/nar/gku1010
Cited by 1,165Open Access
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Abstract

Ensembl (http://www.ensembl.org) is a genomic interpretation system providing the most up-to-date annotations, querying tools and access methods for chordates and key model organisms. This year we released updated annotation (gene models, comparative genomics, regulatory regions and variation) on the new human assembly, GRCh38, although we continue to support researchers using the GRCh37.p13 assembly through a dedicated site (http://grch37.ensembl.org). Our Regulatory Build has been revamped to identify regulatory regions of interest and to efficiently highlight their activity across disparate epigenetic data sets. A number of new interfaces allow users to perform large-scale comparisons of their data against our annotations. The REST server (http://rest.ensembl.org), which allows programs written in any language to query our databases, has moved to a full service alongside our upgraded website tools. Our online Variant Effect Predictor tool has been updated to process more variants and calculate summary statistics. Lastly, the WiggleTools package enables users to summarize large collections of data sets and view them as single tracks in Ensembl. The Ensembl code base itself is more accessible: it is now hosted on our GitHub organization page (https://github.com/Ensembl) under an Apache 2.0 open source license.

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