Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma
Xiuxiu Lu(National Institutes of Health), Kylie J. Walters(University of Minnesota)
Cited by 34
Related Papers
Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13
|Molecular Cell|2009|140
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
|Nature Communications|2017|89
E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure
|Structure|2023|24
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
|Nature Communications|2024|7
An engineered cell line with a hRpn1-attached handle to isolate proteasomes
|Journal of Biological Chemistry|2023|4