Delivery strategies in treatments of leukemia
Tianyuan Ci(Shanghai University of Traditional Chinese Medicine), Wentao Zhang(Zhejiang University), Yingyu Qiao(China Pharmaceutical University), Huangjuan Li(China Pharmaceutical University), Jing Zang(Shanghai University of Traditional Chinese Medicine), Hongjun Li(China Pharmaceutical University), Nianping Feng(Shanghai University of Traditional Chinese Medicine), Zhen Gu(Sir Run Run Shaw Hospital)
Cited by 48
Abstract
pharmacokinetics of drugs, navigating the therapeutics to target cells or the tumor microenvironment and reversing drug resistance, which maximizes tumor elimination and alleviates systematic adverse effects. This review discusses available FDA-approved anti-leukemia drugs and therapies with a focus on the advances in the development of anti-leukemia drug delivery systems. Additionally, challenges in clinical translation of the delivery strategies and future research opportunities in leukemia treatment are also included.
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